The SNARE VAMP7 Regulates Exocytic Trafficking of Interleukin-12 in Dendritic Cells
Interleukin-12 (IL-12), produced by dendritic cells in response to activation, is central click here to pathogen eradication and tumor rejection.The trafficking pathways controlling spatial distribution and intracellular transport of IL-12 vesicles to the cell surface are still unknown.Here, we show that intracellular IL-12 localizes in late endocy